Posted by Hugh on December 2, 2018, at 12:41:33
In reply to Re: Panic attacks, Pain - IV Ketamine Dosing Help Need » Hugh, posted by SLS on December 1, 2018, at 13:46:16
Some people get low-dose naltrexone from compounding pharmacies, but most people make their own liquid LDN. Naltrexone is water-soluble, so dissolve a 50 mg tablet in 50 ml of distilled water and use a medicine dropper to measure the dose. If refrigerated, liquid naltrexone will keep for several weeks.
Your doctor might be willing to prescribe it, or you can contact Crystal Nason, who keeps a list of doctors who prescribe LDN.
https://www.facebook.com/AngelInDisguiseLDN
LDN is usually taken in doses of between 1.5 - 4.5 mg, which can be helpful for some forms of cancer and some autoimmune diseases. But a dose far lower than this could be more beneficial for mood.
Ultra-low-dose naltrexone therapy uses micrograms or nanograms. It's even possible that doses down in the picograms could be helpful.
The lower the dose of naltrexone, the more effective it might be. The following quote is from
"Cotreatment with ultra-low-dose naltrexone at 16.7, 20, or 25 ng/kg, but not at 10 or 200 ng/kg, induced a significant CPP after this 2-h delay. This finding implies that, whereas the rewarding effects of morphine have dissipated by 120 min postinjection, ultra-low-dose naltrexone may extend this effect."
In other words, an extremely low dose of naltrexone enhanced the effects of morphine, and prevented tolerance to it from developing. And it prevented dependence and addiction from developing. A higher, but still tiny, dose of naltrexone didn't have these beneficial effects.
Even people not taking opioids might benefit from taking ultra-low-dose naltrexone, since we all have naturally occurring opioids -- endorphins. An extremely low dose of naltrexone, taken every day, might improve the brain's response to naturally occurring endorphins.
Those interested in trying ULDN should start with a dose of naltrexone in the micrograms. If that doesn't help, lower your dose to nanograms. If that doesn't help, lower it to picograms. Other than the naltrexone, all you need is distilled water to dilute it with and a calculator.
poster:Hugh
thread:1102198
URL: http://www.dr-bob.org/babble/20181024/msgs/1102241.html