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Bad reaction to Trintellix - Again.

Posted by SLS on August 4, 2018, at 7:41:41

In reply to Bad reaction to Trintellix., posted by SLS on July 9, 2018, at 21:22:28

> Hi, All.
> I had a bad reaction to Trintellix. It is hard to describe. Trintellix left me dazed and with anxiety in the pit of my stomach. My mind was numb and it felt like there was some sort of ringing in the center of my head. Inner tension. Dysphoria. All I wanted to do was to lie on the couch and bury my head in a pillow. I tried to sleep all day long. I didnt want to move. It was getting worse day by day. I discontinued the drug a week ago and there are still residual negative effects. They are dissipating slowly. Trintellix has a 66 hour half life.

I restarted Trintellix 10 days ago hoping that I would be able to tolerate it at low dosages. I spent 7 days at 2.5 mg/day. I then raised the dosage to 5.0 mg/day. After 4 days at this dosage, I experienced the same reaction as I described above. I decided to discontinue Trintellix. I'm not sure what to do next. I am frustrated that I am going around in circles with this stuff. I have a feeling that Trintellix has changed serotonin receptor sensitivity. I might not be able to tolerate another serotonin reuptake inhibitor right now.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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