Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Trintellix Label Updated: Improved Processing Spee PeterMartin

Posted by beckett2 on May 6, 2018, at 0:16:17

In reply to Trintellix Label Updated: Improved Processing Spee, posted by PeterMartin on May 4, 2018, at 7:53:00

> Mey 3, 2018
>
> Trintellix Labeling Updated With Data on Improved Processing Speed in MDD
>
> https://www.empr.com/news/trintellix-vortioxetine-major-depressive-disorder-processing-speed-cognitive-function/article/763209/
>
> Lundbeck announced that the Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for Trintellix (vortioxetine) to include data regarding improved processing speed, an important aspect of cognitive function that may be impaired in patients with major depressive disorder (MDD).
>
> The approval was based on data from the 8-week, randomized, double-blind, placebo-controlled studies, FOCUS and CONNECT, which investigated the effect of Trintellix on various aspects of cognitive function among adults aged 18 to 65 years with depression. Study patients were given Trintellix 10mg, 20mg or placebo daily and assessed via the Digit Symbol Substitution Test (DSST), a neuropsychological measure that evaluates processing speed.
>
> In both studies, patients treated with Trintellix had a statistically significantly greater improvement in the number of correct responses on the DSST vs placebo. In addition, depressed mood as assessed by change from baseline in Montgomery-Asberg Depression Rating Scale (MADRS) total score also improved in both studies. The positive effects seen on the DSST may reflect improvement in depression.
>
> Trintellix, a serotonergic agonist and antagonist, was approved by the FDA in September 2013 for the treatment of adults with MDD. Its mechanism is thought to be related to the enhancement of serotonergic activity in the central nervous system (CNS) through inhibition of serotonin reuptake.
>

I'm doing well on Trintellix. After at least two years, I might be finding a higher plateau. Maybe that doesn't make sense. So far, this is the best recovery I've experienced since my life went to sh*t 14 years ago. Trintellix + lamictal.


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:beckett2 thread:1098514
URL: http://www.dr-bob.org/babble/20180331/msgs/1098554.html