Posted by SLS on April 9, 2018, at 15:03:13
In reply to Re: Why is alcohol the only thing that helps me?, posted by Prefect on April 9, 2018, at 11:55:47
> My concern is that it's come to the point I have to drink a whole bottle of whiskey a day in order to function. The more I drink I have to consume more and more since the alcohol is likely desensitizing my GABA receptors and causes a rebound effect where I feel withdrawal and likely suffer from rebound glutamate excitotoxicity when I don't drink.
>
> I need to find an alternative. I'm considering weening off using clonazepam, get off the zoloft, and start taking Fluvoxamine at nights and abilify in the morning to see of it helps.Why are you discontinuing Zoloft and starting fluvoxamine?
Have you tried:
Lamictal
Trileptal
Tegretol
N-acetylcysteine (NAC)Lamictal might increase dopamine (secondary to glutamate release inhibition). Tileptal and Tegretol can reduce glutamate and exitotoxicity. Tegretol can be sedating, which might be good in your case. NAC modulates glutamatergic activity and can increase dopamine, but often takes several months to take effect. Perhaps reducing inflammation is involved. I really don't know. Andrew Nierenberg suggested combining Lamictal with NAC.
Some people do well on a combination of Abilify, Lamictal, and Wellbutrin for severe depression. If you react poorly to Wellbutrin because of anxiety, aggitation, or dysphoria, nortriptyline or a SRI might make a good substitute.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1098005
URL: http://www.dr-bob.org/babble/20180331/msgs/1098044.html