Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Switch from amitrip to noritrip due to poop out? SLS

Posted by ed_uk2010 on March 1, 2018, at 21:51:44

In reply to Re: Switch from amitrip to noritrip due to poop out? ed_uk2010, posted by SLS on March 1, 2018, at 20:53:25

> Would Cymbalta (duloxetine) be of any value?

I think that's a really interesting idea, but it does bring up some potential issues:

1. I don't think duloxetine has been studied much in chronic bladder pain. I did find an abstract from an observational study, but it didn't appear to be effective or well tolerated.

2. Duloxetine can be useful for stress incontinence, but AFAIK, urgency and frequency are much more common in interstitial cystitis.

Anticholinergics, rather than duloxetine, are often useful for urgency/frequency - which could be part of the reason why amitriptyline sometimes reduces these symptoms.

3. I'd wonder whether a therapeutic dose of duloxetine would be an issue while taking paroxetine. Mainly in terms of serotonergic adverse effects.

Just some thoughts really.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:ed_uk2010 thread:1097097