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Re: Hoping Nardil kicks in at 60 (wk3) PeterMartin

Posted by SLS on February 22, 2018, at 2:54:26

In reply to Re: Hoping Nardil kicks in at 60 (wk3), posted by PeterMartin on February 21, 2018, at 22:24:53

> Btw I'm taking it 4 times a day; 6am 8am, 5pm, 8pm. Could there be benefit to take all at once? Doesn't take out the same amount of MAO regardless of peak levels? (I'd assume they'd be higher if I took them all at once)

Is your sleep disturbed? I would consider taking Nardil 3 times a day if it is. 2 @ 6 am / 1 @ 12 pm / 1 @ 3 pm. I don't know any advantage to taking Nardil all at once. In my experience, Nardil acts differently than Parnate. Large doses make me feel weird. I suspect that it upsets the autonomic nervous system. Regardless, it is my suggestion to take Nardil in divided doses.

From the Nardil (phenelzine) monograph:

Initial dose: The usual starting dose of NARDIL is one tablet (15 mg) three times a day.
Early phase treatment: Dosage should be increased to at least 60 mg per day at a fairly
rapid pace consistent with patient tolerance. It may be necessary to increase dosage up to
90 mg per day to obtain sufficient MAO inhibition. Many patients do not show a clinical
response until treatment at 60 mg has been continued for at least 4 weeks.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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