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Re: does viibryd block DAT?

Posted by linkadge on February 2, 2018, at 18:03:33

In reply to does viibryd block DAT?, posted by farshad on February 2, 2018, at 11:41:58

DAT is the dopamine transporter. After dopamine has activated a receptor, it is recycled by DAT. If DAT is blocked, it means that dopamine sticks around longer to activate dopamine receptors.

viibryd blocks DAT weakly. Hence, it is probably not a major part of its effect. However, viibryd may increase dopamine via other mechanisms.

That being said, viibryd is a potent serotonin reuptake inhibitor.





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