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Re: How far is Rapastinel from being approved?

Posted by SLS on February 1, 2018, at 8:30:22

In reply to How far is Rapastinel from being approved?, posted by Lamdage22 on February 1, 2018, at 7:39:19

> Hey folks,
> i am having bad times here. I think tomorrow i will take 75 mg of Trazodone again!
> What about Rapastinel? I may end up trying.

I'm sorry to hear that you are feeling so bad that you should feel it necessary to return to an antidepressant. I know how much you would like to discontinue all of the drugs that you currently take.

As you know, Rapastinel does many of the same things that ketamine does, but has a reduced liability for producing dissociation. That's really its only advantage. Unfortunately, both drugs must be delivered IV. I have some experience with ketamine delivered intranasally. It didn't help me, but it was totally clean. I experienced absolutely no side effects. A friend of mine who, after years and years of treatment resistance to antidepressants, was brought to remission by intranasal ketamine. She was able to discontinue all of the other drugs she was taken. She felt better after only 3 days. Generally speaking, you would know by one or two weeks if it were going to work. It is not worth taking it beyond two weeks. Intranasal ketamine is more widely accepted now.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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