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Re: I have only been psychotic on Nardil. Never withou SLS

Posted by linkadge on November 3, 2017, at 17:55:17

In reply to Re: I have only been psychotic on Nardil. Never withou linkadge, posted by SLS on November 2, 2017, at 7:39:05

Hi SLS,

I was referring to rebound psychosis coming off the antipsychotic, not nardil.

As far as how slowly one should withdrawal from an AP, I have no idea. I suppose it depends on the dose, the potency and the duration of treatment.

I read a book by Solomon H. Snyder (Drugs and the Brain) in which he describes a common euphoric reaction to MAOIs.

This is actually how the antidepressant effects of the MAOIs were discovered. Weren't they originally anti-tuberculosis agents? I think I recall reading that patents were experiencing an elevated mood that was incongruent with simply being cured of TB. It was from the euphoric reactions to MAOIs that the drugs were eventually tested for depression.

In comparison, imipramine was originally tried as an antipsychotic, in which it was ineffective. However, it was subsequently tested in depression in which it was effective.

I guess what I am saying, is that MAOIs can cause an abnormally elevated mood, even in mentally healthy people. As such I (personally) would not read too much into a manic or psychotic reaction.

Linkadge


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URL: http://www.dr-bob.org/babble/20161215/msgs/1095717.html