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Re: Your thoughts SLS?? porkpiehat

Posted by SLS on October 23, 2017, at 15:19:00

In reply to Your thoughts SLS??, posted by porkpiehat on October 23, 2017, at 12:34:15


> Scott can you see a reasonably serious problem with me adding 5-10mgs parnate back after 6 days on Marplan 20-30 mgs? Even combined I'm at less than the target dosage for each.

Your depression is severe and needs to be treated aggressively. I can fully appreciate the disturbances in cognition that you experience. Cognitive impairment is an index of depression severity.

20 years ago, I was desperate enough to combine Parnate and Effexor without my doctor's consent. He was extremely aggressive, but not reckless. I was reckless. I took a single, tiny dose of Effexor while on 120 mg of Parnate. I experienced an episode of serotonin syndrome of moderate intensity that lasted for several hours. The symptoms included muscle rigidity, and I was incoherent.

I am not given to recommending the combining of MAOIs. That's not to say that it can't be done. However, I have never seen it done safely or successfully. For what you want to accomplish, would going up on the Marplan and adding a psychostimulant make sense?

Can you describe the details of your experience with Nardil?

- Scott

> > I'm such a "grass is greener" guy...Kind of regretting the switch to Marplan; why?
> >
> > -I miss the ability to focus and engage on Parnate
> > -parnate took care of my atypical symptoms (rejection sensitivity esp.) way better
> > -I miss my compact 7 hrs of trazodone sleep and waking up ready to go.
> >
> > Again not sure if it's marplan or the parnate levels falling but I'm returning to cognitive problems (can't remember which side my gas tank is on, looking for my car while I'm in it) staying engaged at work, irrational irritability. Negativity.
> >
> > My sense of humor is largely gone as everything feels like a slight. I get super nervous on the phone feeling I have no right to ask simple questions
> >
> > I will soon be fat because I am constantly hungry!
> >
> > I DO NOT MISS...
> >
> > the compulsive fiendish reaction. I haven't had a glass of bourbon or a cigarette in three days, whereas I was chain smoking and drinking about 2 bourbons EVERY DAY for 6 months on Parnate.
> >
> > This weird omnipresent feeling of paranoia and impending danger. I seem to be EXTREMELY sensitive to stimulants.
> >
> > I am take 5-10 mgs of parnate for just enough focus and self-possession to get through work. After four days on Marplan I tried this (5mgs Parnate) on Friday morning and felt weird, scared, confused. A tiny bit of klonopin seemed to clear it up. I can't see how such a low dose of either would be a real danger.
> >
> > I was assuming that doing a hot switch from parnate to Marplan would eliminate the start-up lag as the MAOI levels wouldn't have a chance to dip.

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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