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Re: Parnate Augmentation SLS

Posted by Porkpiehat on August 3, 2017, at 12:14:38

In reply to Re: Parnate Augmentation Alpam, posted by SLS on April 13, 2012, at 2:24:00

> Instead of me making a list of drugs for you to try, I would offer that you begin to make a list of doctors to try. In your doctor's mind, what does the dosage of Parnate have to do with the number of other drugs that you are taking? I don't see the connection.
>
> Parnate can exceed dosages of 120 mg, although I find 80 mg to be optimal. Lots of people experience daytime fatigue with Parnate. Adding a stimulant to Parnate is not particularly dangerous. Neither is adding certain tricyclics (desipramine, nortriptyline, amitriptyline, trimipramine, doxepin). Clomipramine and imipramine must be avoided due to serotonergic activity and the risk of developing serotonin syndrome. Bupropion Wellbutrin; Zyban) is safe, too.
>
> Reducing the dosage of Abilify might not be a bad idea if it is being used to treat depression. It might clear up any cognitive blunting that might be present. I guess you can try adding modafinil instead of a stimulant to treat the daytime fatigue.
>
> I don't blame your doctor for not being comfortable using Parnate in combination with stimulants drugs. He likely was taught that this was strictly contraindicated. That's what is written in standard references. You need to find a doctor who has learned otherwise. You might contact a university teaching hospital to find a doctor or to get a list of referrals.
>
> Believe it or not, Nardil can be less sedating than Parnate.
>
> Lithium at low dosages (300 - 600 mg) makes an excellent augmenter for some people taking Parnate.
>
> There are alternatives available to modify Parnate treatment. You just need to find a more experienced doctor who specializes in treatment-resistant depression (TRD).
>
> Good luck.
>
>
> - Scott
Scott this is an old post, but you referrenced lithium as a good good augmented to parnate. Is this for depression or side effects? I'm finding a low dose 5-10 myself of propranolol is cutting through some of the parnate lethargy and doesn't contribute to beta blocker sleepiness. I'm not in love with having to dose throughout the day to stay awake.


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poster:Porkpiehat thread:1015164
URL: http://www.dr-bob.org/babble/20161215/msgs/1094348.html