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Re: Minocycline good for depression (new small study)

Posted by SLS on July 23, 2017, at 20:31:06

In reply to Minocycline good for depression (new small study), posted by PeterMartin on July 23, 2017, at 16:28:05

When I first started taking minocycline, I experienced a small, but significant improvement in depression. I continued taking it for over a year. Then, I developed dark discolorations of my feet and shins. Hyperpigmentation is a known side effect of minocycline (but not doxycycline). I decided to stop taking minocycline because of this. When I discontinued it, I felt no different. I didn't experience a worsening of depression. My guess is that the positive effect that I felt initially faded slowly with time, and I hadn't noticed it.

Have you ever tried NAC (N-acetylcysteine)? You might try adding it to minocycline. NAC promotes anti-inflammatory processes. Actually, combining NAC with lamotrigine has been suggested by Andrew Nierenberg. Not only is the combination anti-inflammatory, but it is antiglutamatergic. I don't know anyone who has tried all three drugs together.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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