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Re: Norepinephrine and Dopamine Litmus Tests

Posted by linkadge on December 30, 2016, at 7:11:57

In reply to Re: Norepinephrine and Dopamine Litmus Tests linkadge, posted by Prefect on December 29, 2016, at 19:45:03


Luvox may either not be sufficiently helping those symptoms or, alternatively, it may be exacerbating some of them.

Many of the SSRIs can affect sleep quality as well as affect energy / motivation issues. They can also exaserbate GI / IBS problems as they activate 5-ht3 receptors in the gut.

If you wanted a small change, you might ask to change to sertraline (Zoloft). Zoloft has some impact on the dopamine transporter, which may be better for energy / motivation that luvox. Prozac too, tends to be more energizing.

If you wanted a larger change, you could try switching to something like nortriptyline. It can be good for depression / anxiety and sleep and will probably induce less fog, daytime sleepiness, and GI issues.

You might even ask to 'augment' with nortriptyline and possibly try some sort of cross taper if you're on too much of either.

Wellbutrin is another option, but it may have a greater tendency to worsen anxiety than nortriptyline. In general, its good for depression, but not so much anxiety.

Another thoutgh is that the anxiety is related to gaba and not serotonin / norepinephrine at all.





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