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Re: Why isn't nicotine gum used for mood disorders?

Posted by rjlockhart37 on December 19, 2016, at 20:54:52

In reply to Re: Why isn't nicotine gum used for mood disorders? rjlockhart37, posted by Prefect on December 19, 2016, at 20:25:10

When a cigarette is smoked, nicotine-rich blood passes from the lungs to the brain within seven seconds and immediately stimulates nicotinic acetylcholine receptors; this indirectly promotes the release of many chemical messengers such as acetylcholine, norepinephrine, epinephrine, arginine vasopressin, serotonin, dopamine, and beta-endorphin in parts of the brain.[27][28] Nicotine also extends the duration of positive effects of dopamine and increases the sensitivity of the brain's reward system to rewarding stimuli.[29][30] Most cigarettes contain 13 milligrams of inhalable nicotine.[31] Studies suggest that when smokers wish to achieve a stimulating effect, they take short quick puffs, which produce a low level of blood nicotine.[32]" - wikipedia source

that's just a quick reference about it's mechanism of action, nicotine does produce pleasure, but it's not very potent compared to opiates, and methamphetamine which largely influence the dopamine/reward/pleasure center's in the brain

but have they still done blood tests again to see for abnormalties currently?

not a genius but understand pain
"unheard pain is told through good company




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