Posted by Christ_empowered on December 2, 2016, at 14:30:30
In reply to Re: tardive dyskinesia incidence of typical APs?, posted by rjlockhart37 on December 2, 2016, at 13:58:53
I seem to recall reading that low to moderate dose Thorazine produces TD at about the rate of normal dose Risperidone. I think the issue is mostly potency (higher potency often equals more TD), from what little I understand of the subject.
Perphenazine is a mid-potency conventional AP that is often tolerable, when carefully dosed. EPS is more common than Zyprexa, but again: dosing is key.
I read somewhere that loxapine is atypical-ish. I don't know if or how that would affect TD rates. Amoxapine is a TCA antidepressant that is partly metabolized into loxapine, so its an AD+AP, in one molecule+one pill. I read a small abstract of a study in which amoxapine was used for Schizophrenia in Mexico, and it did about as well as Risperidone. I think the amoxapine group had better mood scores, but I could be wrong.
Do you take antioxidants? B-vitamins? I DIY Orthomolecular mostly to prevent TD. So far, so good, and I've been on 30mgs/Abilify plus other meds (mostly anti-epileptics) for 5, 6 years now.
Good luck.
poster:Christ_empowered
thread:1093350
URL: http://www.dr-bob.org/babble/20160928/msgs/1093355.html