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Re: Experiences: Nardil + Cannabis, Caffeine, Nicotine

Posted by Holygeorgizas on July 2, 2016, at 1:24:11

In reply to Experiences: Nardil + Cannabis, Caffeine, Nicotine, posted by Nardilcopter on December 14, 2009, at 14:48:27

To be clear in response to the first follow up post and subsequent comments based on those statements, Nardil as a MAOI is not a releasing agent of dopamine like MDMA, Dextromethamphetamine (meth), or cocaine (which is more specifically a dopamine reuptake inhibitor). It does not function in the same way as that class of drug, and subsequently would not create the same neurotransmitter complications as the user would suggest. As a MAOI, nardil/phenelzine do not release any of the monoamine neurotransmitters, but rather increase their extracellular levels through the unique interaction with the monoamine oxidase enzyme family through inhibition of this activity. To me this seems fundamentally different to a psychoactive substance directly releasing a neurotransmitter. You seem like a well spoken intelligent person nardilcopter, and i think an increase in dose would/could (if you are still on the substance) have been a good idea. From what you write, it most definitely seems that you experienced a manic or hypomanic episode from the nardil alone (thus increasing your drug use overall), and that the lack of effectiveness of the nardil, and complete psychological adversion to the other substances occurred in response to the episode ending.


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URL: http://www.dr-bob.org/babble/20160609/msgs/1090076.html