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Re: Rexulti » SLS

Posted by porkpiehat on April 8, 2016, at 11:10:05

In reply to Re: Rexulti » porkpiehat, posted by SLS on April 8, 2016, at 1:47:31


> Has Buspar improved depression, anxiety, or both? How long did it take to improve anxiety the first time you took it?

Compared to being on nothing but Lamictal, it seemed to increase my motivation and quell a lot of obsessive thinking, which to me feels less depressed. But then when it started turning on me after a week I felt very "sour" and ragey. The day I took it, it slowed my thoughts down quite a bit, but I'm not naive to the drug. I ran four miles for the first time in a year without my brain slipping into a "I can't take this anymore, make it stop" spin-out. Impossible? who knows.


> Yes, prazosin is a norepinephrine NE alpha-1a/b/d antagonist. I haven't ascertained what type of depression it is best suited to treated, though. My depression is bipolar with drug-induced mania. My history is one of chronic multiple traumas
>
My dx is almost identical, but I think my pdoc sees the symptoms as BPII/cyclothymic, but my therapist sees the same things as complex trauma. Same symptoms, different treatments. I'm getting both, which confounds me b.c. one takes serotonergics (potentially helpful in trauma) off the table and mandates neuroleptics to act as AD. With the other I'm ideally on very minimal drugs so I can feel, process, meditate, and drink green tea, and do yoga.

> > I'm contemplating trying trazodone during the day as I can't sleep on it, but I feel great emotionally the next day. Perhaps it would be different with time.
>
> Wow. That is indeed interesting. I hope it works out for you. Let me know what happens.
>
>>>Is it really that peculiar? I can't believe no one else hasn't tried it. I want to try it on a day when I have nothing vital planned. I'm worried that over time it will feel like Serzone which was a lame drug for me, although it stopped my IBS. It almost seemed to work like an MOA inhib. I'm worried about hitting so many neurotransmitters if in fact I am bipolar.

> Just curious - does Remeron make you feel the same agitation and rage that Buspar does?

>>>I took remeron once for two days but i couldn't really work the next day. I think it's really meant for depressed nursing home patients that don't eat, not active young men.
>
> I wonder if Viibryd would work better than Buspar for you, but without provoking rage. Like Buspar, Viibryd is a 5-HT1a partial agonist. However, it is a potent serotonin reuptake inhibitor as well.

>>>I tried Viibryd. At one point I felt very good but I was always tired as hell on it. I think in retrospect it was from Lamictal, which I now think has adverse effects when mixed with a serotonergic (for me, after being on it for 10 years). I felt very disinterested in people I just wanted to stay home and do homework. I also remember being very scattered on it.

I might try again. 37.5 mgs Seroquel knocked me on my *ss for a day (although it turned off the hypervigilance for half a day while I drooled on myself). stopped that last night.

I think my trial process looks like this...see if beta blocker gets me through my panic/tantrums when I get overloaded by tasks or schoolwork-->assuming this is too sedating/impractical, try daytime trazodone with a stimulant safety net-->Try viibryd maybe at night, and without the lamictal to see if that's the problem-->I can try latuda again and hope the nightmares stay at bay and the zoney feeling disappears.

without the AD's I think I've got a better grip/view on my psychological processes and sadness, etc., but I don't know that traditional therapy is going to actually work. I know I can't run a business and go to grad school if I'm flipping out during every exam or screaming at my clients for no reason.
>
>
> - Scott
>
>


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