Posted by SLS on December 14, 2015, at 14:10:31
In reply to Re: Deanxit, posted by Justusphung on December 13, 2015, at 20:54:51
> Strangely, when I was taking pristiq and abilify, I felt more depressed and slept all day long, reluctant to do anything. Then, my pdoc prescribed lyrica 25mg, deanxit once daily, and propanolol 10mg three times a day as to augment the original mediation. I found the deanxit motivating, allowing me to leave my bed. This effect is similar to the one given by amisulpride.
>
> Now, I have stopped taking pristiq, only taking amisulpride 50mg and deanxit twice daily. According to my situation, which other drugs are suitable to help me motivate and calm down?I had never heard of Deanxit (flupentixol/melitracen).
Which type of depression do you have - melancholic depression or atypical depression? Can you describe your symptoms? Do you feel worst in the morning?
How do you react to SSRIs in general?
If you react badly to all serotonin reuptake inhibitors, you may need to look at desipramine, a tricyclic antidepressant (TCA) that is selective for norepinephrine. It will often reduce anxiety when the anxiety is a component of depression - which it often is with melancholic depression. It will not work for GAD. Since melitracen is also a TCA, you might need to discontinue the Deanxit or else try adding a small amount desipramine to see how you react to it.
Since the flupentixol isn't calming you down enough, you might not need it if desipramine works. Besides, I have never been a fan of combination pills. You might need way more melitracen than what you are getting with the Deanxit. However, if you were to take a dosage of Deanxit that would bring your melitracen intake high enough to be effective, the flupentixol would be way too high. It is much better, in my opinion, to dose each drug separately.
Have you ever tried Abilify? If not, it would be interesting to see how you respond to it. If it doesn't cause akathisia, it can actually act like an augmenter of antidepressants and anxiolytic (anxiety-reducing). For me, I felt some restlessness during the first week or so. It was uncomfortable, but disappeared entirely. I would say that the number of people who experience true akathisia represent a minority.
Wellbutrin might be too anxiogenic (anxiety-producing) or agitating for you. I'm not sure.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1084461
URL: http://www.dr-bob.org/babble/20151119/msgs/1084688.html