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Re: Lou's urgent warning-death allowed as supportive » Lou Pilder

Posted by SLS on October 28, 2015, at 9:59:09

In reply to Lou's urgent warning-death allowed as supportive » SLS, posted by Lou Pilder on October 28, 2015, at 9:22:29

You mention that when combining Effexor with Remeron, the levels of certain chemicals are increased dramatically to the point of becoming poisonous. Can you identify which chemicals in particular? I was not aware of this. Many doctors use this combination to treat their most difficult cases. One of the biggest proponents of this treatment strategy is Stephen Stahl, MD. He is very smart and always explains the biological basis of how such combinations work as well as their dangers and side effects. Remeron is not a serotonin reuptake inhibitor, although it does block certain serotonin receptors. I am not aware of any of these receptors acting as autoreceptors that would increase serotonin levels upon their blockade. 5-HT2a/c and 5-HT3 are the receptors cited as being affected by Remeron. Serotonin syndrome does not seem to be a problem, despite two reports appearing on Medline (Pubmed), one of which included the coadministration of tramadol, a known serotonin reuptake inhibitor.

Clever subject line.

:-)


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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