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PDE4 inhibitors?

Posted by SLS on July 22, 2015, at 9:06:22

Does anyone know of a drug available in the USA that inhibits PDE4?

I just read something suggesting that increasing cAMP levels effectively treats depression. A PDE4 inhibitor would do this. The only PDE4 inhibitor that I know of is a Japanese antidepressant by the name of rolipram. I don't think that it is a very effective drug by itself, but might make a good adjunct. If it were available in the USA, I would try it.


- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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