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Re: Reserpine » linkadge

Posted by SLS on July 9, 2015, at 14:59:56

In reply to Reserpine, posted by linkadge on July 7, 2015, at 18:32:00

> This seems like a promising treatment for mania, psychosis, and possibly mixed states / insomnia.
>
> It can induce depression (in higher doses).
>
> Google this substance - but caution, it depletes monoamines (mainly dopamine and norepinephrine).

There is some old literature about the use of reserpine for various psychotic states. It didn't seem to garner much support by the medical community as a clinical treatment. I don't remember why. One rather interesting proposal for the treatment of depression was to administer reserpine first, followed by a TCA. Perhaps it somehow changes the function of storage vesicles. That's just a wild guess.

Medline / PubMed isn't working for me right now. You should find some titles, but probably not necessarily the abstracts. I'll check out Google.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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