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Re: How strong is Clonazepam really? » Phillipa

Posted by ed_uk2010 on January 9, 2015, at 9:47:29

In reply to Re: How strong is Clonazepam really? » phidippus, posted by Phillipa on January 8, 2015, at 19:51:27

>20mg for seizures only. Phillipa

In theory. It's not clear what the maximum dose should be. In the UK the maximum recommend dose for epilepsy is 8mg per day, but clonazepam is not widely used in epilepsy... It's too sedating, tolerance develops to its anti-epileptic properties over time and high doses often produce psychiatric disturbances in epilepsy, as well as rebound seizures on attempted withdrawal. There are better choices for most people with epilepsy, but benzodiazepines retain a vital place in the acute treatment of prolonged seizures, and for temporary 'cover' while adjusting other meds.

In psychiatry, it's usual to avoid more than 4mg per day here, and more than 2mg per day is rarely prescribed beyond the acute phase of illness. Up to 1mg per day is probably optimal for most types of generalised anxiety, and 1-2mg for panic disorder +/- agoraphobia. Older people are often treated with less eg. 0.25mg once or twice a day.


 

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