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Caution » ed_uk2010

Posted by ed_uk2010 on December 10, 2014, at 20:58:07

In reply to Re: Laughing gas studied as depression treatment, posted by ed_uk2010 on December 10, 2014, at 19:09:31

>What goes up must come down....

Apologies if that was misinterpreted. It was intended entirely for purposes of amusement :) The study is clearly interesting but requires some context (in my opinion).

Bearing in mind that nitrous oxide (N20) is a known euphoriant.... I do tend to feel that any allegedly persistent 'antidepressant' effects found in trials such as this should be questioned very carefully. Patients may feel better briefly after treatment, perhaps as a result of remembering what it's like to feel pleasure (?). The issue as I see it is that it seems highly unlikely that any apparent benefits would continue long-term. Problems, on the other hand, seem likely. The same applies to other euphoriant drugs sometimes purported to exert antidepressant effects. Depression of mood is likely in the long run... amongst many other issues related to addiction.

 

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URL: http://www.dr-bob.org/babble/20141120/msgs/1074131.html