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Bad reactions to all antidepressants?

Posted by BusuB on October 14, 2014, at 12:50:37

So as the title says, I've been having a lot of trouble for the past year and a half finding a medication that will adequately control my generalized anxiety and depression. Since February of 2013 I've been trialing medications. So far I've tried each of the following: escitalopram, venlafaxine, clomipramine, fluoxetine, duloxetine, vortioxetine and now citalopram. Each medication trial was at minimum 8 weeks (up to 6 months on escitalopram). However, each one except for clomipramine causes me to have terrible early morning insomnia and an inner restlessness that can only be described as mild akathisia that can vary in intensity day to day. They've all differed in mild ways, for instance on fluoxetine, I'd wake up trembling and mild panic, with citalopram, I wake up with extreme restlessness in legs and arms. My health anxiety and general worry about external things are under control but I find myself focusing on how I feel quite a lot. Bottom line I just feel extremely uncomfortable in my body with these antidepressants. I'm on week 8 of citalopram right now (week 5 of current dose of 20) and I'm ready to throw in the towel.

Is there a reasonable explanation for why I feel this way on antidepressants? I have tried med free between vortioxetine and citalopram but quickly found that I need something to control my worry and depression (about 6 weeks post withdrawal I was bawling in my docs office). Back to clomipramine, just made me extremely fatigued, constipated and numbed my genitals the whole time I was on it. Some restlessness but not as extreme.


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poster:BusuB thread:1072226
URL: http://www.dr-bob.org/babble/20140914/msgs/1072226.html