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Re: Best Painkillers for Resistent Depression?

Posted by Octothorpe on August 1, 2014, at 11:07:11

In reply to Best Painkillers for Resistent Depression?, posted by AlexCanada on June 19, 2014, at 2:10:21

I've had experience with hydrocodone 10/325 Apap for about 3 years. I started with 1 - 3x/day. The first six months were pretty good, it really helped with anxiety and so with reduction in anxiety came a better mood. At 6 months, I developed tolerance and decided to quit. I tapered off fine, but then decided I needed the hydrocodone. As I had a bunch of pills left, I quickly upped my dose to 8 pills/day. My psychiatrist, to my surprise, increased my dosage to that amount. Keep in mind I have had TRD and anxiety all of my adult life-it's not like this was my first option. I have finally tapered off again and will not re-start. They are physically and psychologically addictive. Was the 6 months of relief worth it? In my opinion yes. Be aware though that it is only a temporary crutch and you will face physical dependence, making it hard to quit unless you taper very carefully. I think the reason I could quit this time is I have hope/availability of other treatments-intranasal ketamine, oxytocin, dextromethorphan and low-dose naltrexone. Without hope opioids are going to be very hard to quit, and if you are prone to addiction they could very well ruin your life. Not a drug to be taken lightly.

Sorry for the long post. My best to you.


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