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Re: Serzone or Trazodone for Depression? » mogger

Posted by softheprairie on June 16, 2014, at 3:36:13

In reply to Serzone or Trazodone for Depression?, posted by mogger on June 9, 2014, at 11:09:47

Sorry I am late to the game, but I saw this and can answer, since I am taking the nefazodone. It is working well for me, and my liver is okay so far. I have been on many, many antidepressants and combinations of meds from various classes (even up to MAO inhibitor), so it is justified. Just before this one, I was pleased with the high dose desipramine, and was on it for a few years I think, but I developed a horrible urinary pressure problem from it, and was not willing to live with that. I was on no main antidepressant there for a little bit after that (just the adjuncts of perphenazine and liothyronine), but depression worsened until I stressed insistently to the pdoc that I needed a new antidepressant, and this is the one he mentioned and I went with. We did a gradual increase, but at a bigger dose I started to get the same urinary pressure feeling (even after just urinating), so we brought the dose of nefazodone back down to 100 mg twice a day, and that is something I can live with, and my depression feels pretty well-treated to me.

Trazodone I can't speak to that much, since I have not tried it. I do have a general low energy/fatigue thing going on as my norm, so I don't think I'd want more tiredness during awake times that trazodone usually causes. I don't think I get much fatigue from the nefazodone, so that is good.

 

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