Posted by phidippus on April 14, 2014, at 14:10:18
In reply to Re: Risperdal Questions again » phidippus, posted by iowamoo on April 12, 2014, at 16:19:21
> Can you give an example of each with say Lamictal vs Risperdal on how one would be different for lack of a better word on each med?
Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs. It is a triazine derivate that inhibits voltage-sensitive sodium channels, leading to stabilization of neuronal membranes. It also blocks L-, N-, and P-type calcium channels and has weak 5-hydroxytryptamine-3 (5-HT3) receptor inhibition. These actions are thought to inhibit release of glutamate at cortical projections in the ventral striatum limbic areas, and it has been pointed out this neuroprotective and antiglutamatergic effects as promising contributors to its mood stabilizing activity.
Risperidal has been classified as a "qualitatively atypical" antipsychotic agent with a relatively low incidence of extrapyramidal side effects (when given at low doses) that has more pronounced serotonin antagonism than dopamine antagonism. It has actions at several 5-HT (serotonin) receptor subtypes. These are 5-HT2C, linked to weight gain, 5-HT2A, linked to its antipsychotic action and relief of some of the extrapyramidal side effects experienced with the typical neuroleptics
Eric
poster:phidippus
thread:1063911
URL: http://www.dr-bob.org/babble/20140328/msgs/1064187.html