Posted by tom2228 on March 30, 2014, at 20:41:15
In reply to Re: Options for ADD while on Nardil » tom2228, posted by SLS on March 29, 2014, at 14:49:26
> > > > > maybe a low(ish) dose of desoxyn? kinda a long shot, but I seem to recall desoxyn being the preferred stimulant for some patients on MAOI drugs.
> > > >
> > > > Serotonin syndrome?
> > > >
> > > >
> > > > - Scott
> > >
> > > not that anecdotes are much to say about safey but I haven't had any problems with SS while on Desoxyn + MAOIs for 3.5 years. I also (unfortunately; am in my right mind now and I do not recommend) used street m-AMP on a binge basis on up to 40mg Marplan without complications (besides severe mania/ psychosis).
> > >
> > > Have you ever tried Desoxyn, Scott? Been meaning to ask you. It's a pretty good option IMO to augment other ADs for depression/ anxiety/ energy, especially if you've tried everything else and other stims. Qualitatively different from other stimulants.
> >
> > I would like to add that although I am on 5-HT2a blockers (AAPs and soon nortriptyline) that I didn't have problems with serotonin syndome with that combination before I was on the 5-HT2a antagonists.
>
> Thanks for sharing your anecdote. Very interesting. I have never thought to use Desoxyn. Thanks for the idea.Glad I could give you another option to think about. Just when you think you've tried everything...
> I don't think I would broach the subject with my doctor until I am off of Parnate.
Are you planning to come off Parnate?
I'm not sure that would be necessary since you are taking Abilify and Nortrip, which both have 5-HT2a antagonism. As you may know, cyproheptadine, a 5-HT2a antagonist, is often used to treat SS.
from Dr. Bob's psychopharm tips "MAOIs in high doses and with stimulants":
Dr. Caldwell:
"I put the pt in the ICU and added very slowly Dexedrine or Desoxyn to the patient's regimen. It was wonderful -- a grand remission occurred -- and complications were zero. I've tried it since a few times, starting a low doses and titrating gradually upward, and each time no complications arose. Like all treatment efforts, it has been variably effective, but definitely worth trying."I've seen you say you tend to get a premonitory "feel" for new meds in the earliest of stage. So I must say, if you should try it, Desoxyn is unlike other stims in that it takes 2 weeks for the actual effect to show. You would have to give it time and may be disappointed if you qualify the effect before then or solely on an acute usage basis. And I would caution to start low and go slow rather than starting higher because you can tolerate it: (1) Avoiding tolerance once the correct dose is found is important with this med, and (2) I notice that anything over my "sweet spot" and I tend to feel worse, perhaps more depressed.
>
> I hope you continue to feel better and better.
>
Thank you, I wish you the same and best of luck.
>
> - Scott
poster:tom2228
thread:1063351
URL: http://www.dr-bob.org/babble/20140328/msgs/1063446.html