Posted by phidippus on March 2, 2014, at 19:03:54
In reply to Re: Sudden sensitivity to SSRIs/side effects?, posted by Dispossessed on February 28, 2014, at 20:51:44
> The akathisia is a feeling of mild panic/unease
coupled with an overwhelming desire to move my legs and armsThese could be just panic symptoms. When I have panic attacks I get the same kind of motor agitation.
The problem for you is SSRIs and Clomipramine are the most widely studied medications used to treat OCD. It is widely acknowledged that OCD is a result of a depletion of serotonin in key areas of the brain. It is also believed that excess dopamine is also involved in the pathonogenises of OCD-especially an excess of dopamine in the nucleus accumbens, which is the target of novel therapies for OCD namely deep brain stimulation. Other theories for the root cause of OCD involve glutamatergic models which have been studied-Topomax and Riluze, both anti-glutamatergic, have shown promise in the treatment of OCD, but these medications are always used alongside an SSRI.
If you want to treat your OCD appropriately, you need to take an SSRI to fix the serotonin imbalance in your brain. If you don't get enough response, you add a low dose AP. Then you add an anti-glutamatergic.
You need to find a way to treat the akathisia so you can take an AD or you're going to get nowhere.Eric
poster:phidippus
thread:1061454
URL: http://www.dr-bob.org/babble/20140214/msgs/1061695.html