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Re: Deep TMS more effective than rTMS (article)

Posted by Zatar on February 11, 2014, at 8:14:55

In reply to Re: Deep TMS » SLS, posted by Zatar on February 11, 2014, at 8:07:34

Now I'm wondering if simply switching to deep TMS for once a month maintenance therapy will be enough. I'm still willing to try it.

-Zatar


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280107/

Neuropsychiatr Dis Treat. 2012; 8: 5564.

ECT, rTMS, and deepTMS in pharmacoresistant drug-free patients with unipolar depression: a comparative review

Results

The comparative evaluation of HDRS percentage variations shows ECT as the most effective method after 4 weeks of therapy; on the other hand, a better efficacy is obtainable by deepTMS after 2 weeks of therapy. DeepTMS is the technique that gives the best improvement of cognitive performances. The percentage of remitted patients obtained with ECT treatment is the same obtained in the deepTMS group. Both techniques have a remitted patients percentage two times larger than the rTMS. DeepTMS shows a tolerability, measured by the number of dropped-out patients, worse than ECT.

Conclusion

Our investigation confirms the great therapeutic power of ECT. DeepTMS seems to be the only therapy that provides a substantial improvement of both depressive symptoms and cognitive performances; nevertheless it is characterized by a poor tolerability. rTMS seems to provide a better tolerability for patients, but its therapeutic efficacy is lower. Considering the small therapeutic efficacy of deepTMS in the last 2 weeks of treatment, it could be reasonable to shorten the standard period of deepTMS treatment from 4 to 2 weeks, expecting a reduction of dropped-out patients and thus optimizing the treatment outcome.


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