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Re: ssri's/snri/s

Posted by linkadge on January 26, 2014, at 13:20:19

In reply to ssri's/snri/s, posted by joe f on January 26, 2014, at 11:59:15

No, each SSRI is an entirely different chemical - except in the case of isomer or metabolite drugs (citalopram / escitalopram, venlafaxine / desvenlafaxine).

Luvox, for example, has no relation to Paxil. The two drugs just happen to have affinity for common targets (namely the serotonin transporter), but that's where the similarity ends. Luvox is a sigma agonist, which paxil is not. Paxil has affinity for the norepinephrine trasporter, which luvox has negligible affinity. There are other individual differences as well.

Linkadge


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URL: http://www.dr-bob.org/babble/20140123/msgs/1059561.html