Posted by phidippus on January 23, 2014, at 20:21:36
In reply to cymbalta+lithium+? some advice please, posted by Elanor Roosevelt on January 23, 2014, at 19:16:15
Anhedonia is usually a symptom of depression. Anhedonia is defined as the inability to experience pleasure from activities usually found enjoyable, e.g. exercise, hobbies, music, sexual activities or social interactions.
Researchers theorize that anhedonia may result from the breakdown in the brain's reward system, involving the neurotransmitter dopamine. Studies by Paul Keedwell, MD, then of King's College, found that the brains of participants who were clinically depressed had to work harder to process rewarding experiences. While earlier research believed dopamine to be primarily involved in the subjective experience of pleasure, the last 20 years has seen a conceptual shift, such that dopamine is now believed to underlie various aspects of reward anticipation, learning, and motivation.
My best advice would be to isolate whether the Cymbalta or the lithium is causing your anhedonia. I would stop the Cymbalta and assess who you do off of it.
Eric
poster:phidippus
thread:1059366
URL: http://www.dr-bob.org/babble/20140123/msgs/1059375.html