Posted by ed_uk2010 on December 10, 2013, at 14:32:22
In reply to cogentin » ed_uk2010, posted by g_g_g_unit on December 9, 2013, at 2:24:59
>Hey ed, wikipedia lists the half-life of Cogentin as 12-24 hours .. I'm a bit confused, because people most commonly seem to be dosing b.i.d.
Can be taken once or twice a day, depending on response. Half lives vary between individuals so perhaps it was wrong of me to suggest that the timing of the dose won't matter after a few days.
>I read it acts as a DRI at the 'nerve terminals', and have no idea what that means; but I've actually noticed some psychoactive effects that I thought might be consistent with a DRI .. namely, I've been hyperfocusing far more, my obsessive thoughts are much 'louder' and distracting, and my sleep is disturbed (I take it at 6pm and find it calming for about 3 hours, before stimulation takes over) though I'm still alert and focused during the day. I feel less 'stressed'.
Yes, I believe it is a weak DRI. Would it be worth trying a different anticholinergic? In Aus you have benzhexol (Artane) and biperiden (Akineton). Artane has a reputation for being stimulating. Biperiden might be more suitable.
Have you tried the atenolol yet?
poster:ed_uk2010
thread:1055049
URL: http://www.dr-bob.org/babble/20131209/msgs/1055911.html