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Re: Prozac Derealization But Improved OCD Exisessentialist

Posted by doxogenic boy on November 23, 2013, at 9:02:12

In reply to Re: Prozac Derealization But Improved OCD, posted by Exisessentialist on November 22, 2013, at 21:22:51

> I believe the pregabalin is assisting with the anxiety as I'm at least able to express negative opinions, something I'm not used to even being able to consider expressing. If all of the SSRIs made my condition worse, is it worth trying clomipramine for OCD or depression?

That's a good question. Clomipramine is probably the only TCA that works for OCD, because of its serotonergic effects, so there is a risk of worsening the condition. When this happened on SSRIs, how long did it last after you stopped taking them before the side effects went away? Could you try clomipramine for a short period of time, and then stop if it worsens the depersonalization syndrome?

> I've also tried nortriptyline for depression in the past but it was in combination with sertraline and tryptophan. I'd be interested in seeing what it does without the serotonin modulators.

If you don't take a serotonergic antidepressant, do you think your OCD will become considerably worse, and could you handle that with exposure and response prevention therapy? Then it would be easier to treat the depersonalization, if all serotonergic antidepressants worsen it.

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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poster:doxogenic boy thread:1053210
URL: http://www.dr-bob.org/babble/20131115/msgs/1054794.html