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Re: Parnate (tranylcypromine) ... starting to work

Posted by Snell on October 21, 2013, at 11:03:07

In reply to Parnate (tranylcypromine) dose, posted by Snell on October 6, 2013, at 14:17:34

Again, thank you everyone. On October 16, at 40mg/d, I started feeling a response. For one thing, my dreams started being very vivid, and I would wake up after each one (it was like going to a quadruple feature). Then during the day I noticed I felt more positive and had more energy.

That stayed like that for a couple of days--no "recovery," just feeling slightly less bad--and I increased the dose to 60 mg/day on Saturday. Now I can say I've recovered--I'm able to work a full day, the paralysis is gone, my anxiety is much lower, I'm able to "approach, not avoid." Don't worry, if it switches into mania I'll back off on the dose and I have plenty of Seroquel and Depakote.

I know that this pattern is what's supposed to happen--you start the drug and get an immediate reaction that fades after a couple of days, then there's several weeks of nothing, then the drug starts to "really" work if it's going to work. I've just never had that experience with any other antidepressants. With everything else, if it was going to work, it started working almost immediately--I've never had this classic six-week waiting period. I think that's why I started the thread with "... failure?"

I have heard, not only from the gentleman here, but elsewhere, that this drug likes to poop out between 6 and 18 months after it starts. Well, I'll take all the functioning I can fit in.

I certainly don't think I'll need to go above 60mg/d.


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Psycho-Babble Medication | Framed

poster:Snell thread:1051793
URL: http://www.dr-bob.org/babble/20130930/msgs/1052692.html