Posted by phidippus on October 1, 2013, at 15:55:30
In reply to Re: Savella, posted by LouisianaSportsman on October 1, 2013, at 14:55:36
Riluzole inhibits the release of glutamic acid from cultured neurons, from brain slices, and from corticostriatal neurons in vivo. It is thought these effects may be partly due to inactivation of voltage-dependent sodium channels on glutamatergic nerve terminals, as well as activation of a G-protein-dependent signal transduction process. Riluzole also blocks some of the postsynaptic effects of glutamic acid by noncompetitive blockade of N-methyl-D-aspartate (NMDA) receptors.
Eric
poster:phidippus
thread:1051278
URL: http://www.dr-bob.org/babble/20130930/msgs/1051521.html