Posted by Tomatheus on September 27, 2013, at 23:53:15
In reply to Bone Protein May Influence Cognitive Decline, posted by Phillipa on September 27, 2013, at 18:28:10
It seems that a metabolite of vitamin D3 (1,25-(OH)2D3) can increase the synthesis of osteocalcin:
http://www.ncbi.nlm.nih.gov/pubmed/3873510
http://www.jbc.org/content/260/15/8706.full.pdf
This evidence that osteocalcin may influence brain health seems like it could very well be yet one more reason to supplement with vitamin D and/or increase sun exposure (sensibly, of course), especially for those whose blood levels of the vitamin are deficient or insufficient. It would at least make sense that if one is low in vitamin D that one is also probably going to be low in both 1,25-(OH)2D3 and osteocalcin. It also makes sense that increasing one's vitamin D intake should likely reverse these problems.
T.
Conditions:
* chronic fatigue, hypersomnia, and related symptoms
* schizoaffective disorderTaking Abilify, niacin, vit. D
poster:Tomatheus
thread:1051366
URL: http://www.dr-bob.org/babble/20130828/msgs/1051377.html