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Re: Phentermine + more.depressed? » alchemy

Posted by SLS on July 31, 2013, at 7:40:33

In reply to Re: Phentermine + more.depressed?, posted by alchemy on July 16, 2013, at 23:28:10

> Stimulants initally give me a mood and motivation boost. I have only taken Phentermine a few days and am hoping that is the reason for a worsened mood.
> I guess phentermine is also a stimulant but only works on NE. I know it is not suppose to help your mood, but why might it worsen it when it is in the stimulaints class?

I think phentermine works more on the hypothalamus than the other stimulants. Sometimes, more is less. As an example, increasing the activity at Brodman 25 produces depression while decreasing it acts as an antidepressant. This is how DBS works.

Looking at synaptic neurotransmitter levels is important. However, with the brain, it's location, location, location. The brain is a network of circuits and processors as well as a pool of neurochemicals.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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