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Re: Ketamine...whoa!

Posted by linkadge on July 22, 2013, at 21:33:43

In reply to Re: Ketamine...whoa!, posted by SLS on July 22, 2013, at 17:13:30

Low dose = glutamate release decrease
- Intermediate dose (therapeutic) = glutamate release increase
- High dose = glutamate release decrease

Lithium within a certain dose range has similar actions. In certain dose ranges it decreases glutamate re uptake and in others it enhances it. I read somewhere that ketamine might be acting through a gsk-3b dependent mechanism.

Linakdge


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URL: http://www.dr-bob.org/babble/20130706/msgs/1047652.html