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Re: Best meds for dysthymia

Posted by tecknohed on June 19, 2013, at 17:15:59

In reply to Re: Best meds for dysthymia » SLS, posted by Beckett on June 19, 2013, at 16:38:00

I thought everyone knew that Nardil manipulated GABA in a positive way. When I was on Nardil & 1.5mg clonazepam, I decided to stop the benzo. And my pdoc reasured me that being on 90mg Nardil meant I could simply stop the clonazepam without tapering. He was right. From what I remember one of Nardil's metabolites is responsible for its pro-GABA effects.
I now take the MAOI Marplan (isocarboxazid), another hydrazine derivative but which has no such effect on GABA. Hence why I need 4mg clonazepam daily.


Social Phobia, Major Depression (TRD)
Isocarboxazid 90mg
Clonazepam 4mg
Bupropion PR 300mg
Quetiapine MR 100mg + 25mg IR at night
Amitriptyline 100mg
+ Particular Supplements


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