Posted by Hugh on April 13, 2013, at 13:50:54
This study combined 15 mg of buspirone with 3 mg of sustained-release melatonin. Alone, neither had any antidepressant-like action, but combined, they were very effective.
http://www.ncbi.nlm.nih.gov/pubmed/22998742
This single case study used 5 mg of buspirone combined with 3 mg of melatonin on a woman who had bipolar 1 and treatment-resistant depression.
http://www.alphagalileo.org/viewitem.aspx?itemid=62284&culturecode=en
I took buspirone briefly in the late '90s, and it caused suicidal ideation, so I won't be trying this combo. But I told my mother about it last year, and she tried it, I think at 5 mg of buspirone and 3 mg of SR melatonin. Her depression improved, but she stopped taking it after a few months because it made her insomnia worse. But it did help to lift her out of a pretty deep depression.
poster:Hugh
thread:1042114
URL: http://www.dr-bob.org/babble/20130408/msgs/1042114.html