Posted by SLS on January 30, 2013, at 6:52:35
In reply to Re: Nationwide ketamine trial for depression » Bob, posted by johnLA on January 30, 2013, at 0:47:01
> bob-
>
> the amount that they are using for depression is about 5% of what is used on the street to get a high.
>
> i did a ketamine infusion this past summer. very very mild buzz. lasted about an hour or so after. then, nothing.
>
> and, it didn't lift my depression.
>
> not sure what amount they will use in injections, but i would assume it's the same protocol as the infusion (based on weight).
>
> hope bryn finds some relief.
>
> johnThere is a rather low dosage window within which ketamine acts as an antidepressant, and must be carefully administered in order to maintain this window - thus the infusion administration (0.5 mg/kg body weight given over 40 minutes). If you take too much, it doesn't work. I believe the blood level should be maintained around 200 ng/ml. This might translate to an oral dose of only 0.5 mg/kg body weight. Benzodiazepines are thought to reduce the efficacy of ketamine for depression.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1036666
URL: http://www.dr-bob.org/babble/20130124/msgs/1036854.html