Posted by ikasug on December 11, 2012, at 11:58:59
In reply to Re: About to begin PARNATE » Trevpr, posted by SLS on December 3, 2012, at 9:51:31
I responded to Parnate when I tried it this summer, but unfortunately, I was not able to continue increasing the dose past the FDA limit of 60mg.
Initially it did feel stimulating, but not especially so. It was more like a lot of caffeine, or night-before-the-big-day jitters than a heavy stimulant.
The antidepressant effect did not kick in for almost a month. When it did kick in, I felt noticeably more competent and confident, followed by a sense of palpable well-being. If you pay lots attention to how a drug feels in your body, as if you were expecting a 'high,' there is definitely a change. It is not intense, though I had a few days of self-induced euphoria when I noticed that I was not nearly as depressed as I had been.
Unfortunately I still felt mostly down, but it was able to bring me out of one of the worst periods of my life. It made itself known mostly by the weight loss (a good thing, I lost 70 lbs in about 4 months after a disastrous run on Remeron) and by how much I got accomplished. Unfortunately Parnate did not do much for my anxiety and seemed to have pooped out after a while at the 60mg FDA limit (pdoc would not increase past this limit).
As far as side effects, the only one I really had was unbelievable orthostatic hypotension. It made itself apparent immediately as soon as I titrated to 30mg, though I did a speedy titration. Even when I was at 60mg for over a month I was still dizzy standing up. This has not happened to nearly the same extent on Nardil.
I find that on MAOIs if I eat too much of a no-no food I do not have a full-blown blood pressure reaction, but the boost in NE becomes stimulating. Something to watch out for.
poster:ikasug
thread:1031899
URL: http://www.dr-bob.org/babble/20121130/msgs/1032832.html