Posted by SLS on September 29, 2012, at 18:12:18
In reply to Jono and/or SLS, posted by ChicagoKat on September 29, 2012, at 16:07:38
> I am becoming hesitant about adding Nortryptiline to Nardil b/c I know Nortryp. hits NE receptors hard, which can lead to an increase in anxiety in those predisposed to it, which I am. In fact, I think that is why Ritalin ended up causing me so much anxiety that I can no longer use it.
>
> So I wondered if either of you, or anyone else for that matter, had any suggestions of ADs that are safe with MAOIs but that hit NE less.
>
> Thanks for any ideas.
> Kat
My only worthwhile advice at this juncture is not to get "too smart". Nortriptyline can reduce anxiety when it hits the right targets for some people. It does antagonize 5-HT2a receptors. Even desipramine can reduce anxiety if the anxiety is integral to the depressive disorder being treated. If you have never tried a tricyclic before, you might consider trying nortriptyline first and add the Nardil afterwards if necessary. Doing things in the reverse order is counseled against, although I have never seen a compelling argument for this. I have added a tricyclic to ongoing MAOI treatment a few times without sequelae.Parnate is more forgiving with respect to side effects, especially when combined with a tricyclic. The combination of Nardil with a TCA can produce increased hypotension and urinary retention.
I am not smart enough to predict how you will react to any of these treatments. You might experience few if any side effects with combining Nardil and nortriptyline. Then again, nortriptyline might increase your anxiety. I really don't know. Adding Wellbutrin to Nardil sounds interesting. It should be safe. Some people here have tried it. I have added Wellbutrin to ongoing Parnate treatment. Of course, some people do experience intolerable anxiety and irritability with Wellbutrin monotherapy.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1027029
URL: http://www.dr-bob.org/babble/20120922/msgs/1027042.html