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Re: ANHEDONIA - Questions and Answers

Posted by Trevpr on September 23, 2012, at 20:22:27

In reply to Re: ANHEDONIA - Questions and Answers, posted by jono_in_adelaide on September 23, 2012, at 20:00:19

Do you guys know of any articles or literature pointing to it being okay to mix Parnate with Wellbutrin, protriptyline, or nortriptyline to show to my psychiatrist?

Intuitively it makes sense to me, since these drugs are not serotonergic and won't cause serotonin syndrome, but they are apparently contraindicated so my doc will probably not let me unless there is something to back it up. A stimulant+maoi might be good I'm thinking; so far the norepinepherine drugs (Wellbutrin, protriptyline, desipramine) haven't done a single thing, and basically to me feel like placebos with minor side effects. I've really wanted to try Parnate or selegiline.

Anyone build up a tolerance rapidly to stimulants? I noticed after the first week or two all they did was PHYSICALLY give me energy without any impact on my mood, anhedonia, or emotions. Basically after a week they just elevated my heart rate. At first there were minor improvements in mood, motivation, and emotional response, which wasn't much, but believe me, any improvement is a breath of fresh air. Elevating the dose is not an option. I stupidly raised it on my own without any change, but then my heart rate got too high and I had to go to the ER.

SSRIs sound like a bad idea, for reasons I mentioned in my first post, unless they possess extra qualities like 5HT1a/2a/2c antagonism or something, such as low dose prozac, but even that seems to be pretty weak.

I just don't get why everyone else seems to notice SOMETHING from taking these antidepressants, while I don't? I am beginning to feel like they work by the placebo effect and I'm unfortunately the only one smart enough to not be affected by it because I'm so analytical or something, lol. I really hope that isn't the case.

And what about libido? I'm in my prime here and still single. I'd rather not miss these years and/or end up alone. I don't just mean sex, I mean romantic attraction or attraction of any kind. I just feel...."blah" towards it all. Does it come back? It's been gone for almost 11 months now with no signs of changing... Man this sucks big time.


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poster:Trevpr thread:1026437
URL: http://www.dr-bob.org/babble/20120922/msgs/1026460.html