Posted by sk85 on September 21, 2012, at 17:05:35
I've been getting some really good results with combining low dose clomipramine 10-20 mg with yohimbine (yohimbe extract). On its own 10-20 mg clom does nothing for depression, but yohimbine add-on seems to really really pull me out of the blues when they hit me. However, it does make me feel somewhat worse the first 2-3 h after taking it, but after that it completely reverses direction. The crappy feeling does show tendencies for being reduced over time. Anyway, has anyone else ever used yohimbine for mood issues?
PS. Yohimbine can produce toxic effects with some other tricyclics, e.g. imipramine.