Posted by SLS on August 26, 2012, at 11:09:32
In reply to Lou's request-krduhbillehty » SLS, posted by Lou Pilder on August 26, 2012, at 10:05:44
I like this one. Although the article is old, it probably includes more cases than any other study you will find. It was written at a time before SSRIs became available, and MAOIs and tricyclics were about the only antidepressants available. Doctors at the time were much more informed and comfortable with their use than today. Combining MAOIs and tricyclics were not strictly forbidden. My first introduction to this treatment modality occurred in 1983. It was then that my doctors at Columbia treated me with a combination of Nardil and amitriptyline. I have been prescribed tricyclics with MAOIs on and off for the last 30 years without incident. Recommendations for this treatment were made to me by doctors at Columbia, NYU, NIMH, Beth Israel, Harvard, and Princeton.
- Scott
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http://www.ncbi.nlm.nih.gov/pubmed/942286
"Arch Gen Psychiatry. 1976 Jul;33(7):828-30.
Combining tricyclic and monoamine oxidase inhibitor antidepressants.
Spiker DG, Pugh DD.
AbstractThe charts of 150 inpatients and 51 outpatients treated with a monoamine oxidase inhibitor (MAOI)-tricyclic antidepressant combination were reviewed. The incidence and severity of side effects among the patients on the combined regimen were essentially the same as those seen in the control groups. There were no deaths or strokes resulting from use of this regimen. The most frequent troublesome side effect was orthostatic hypotension. We conclude that the use of a MAOI-tricyclic combination in oral therapeutic doses is safe. However, the efficacy of this combination has not yet been proved, and it may be particularly toxic if taken in an overdose."
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1024162
URL: http://www.dr-bob.org/babble/20120818/msgs/1024245.html