Posted by brynb on August 24, 2012, at 1:59:28
In reply to Re: Selegiline-good for depression and anti-aging?, posted by SLS on August 24, 2012, at 1:27:49
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> Serotonin syndrome is almost guaranteed when a SRI is combined with an MAOI. I really would have liked to have tried tramadol, but I won't go near it because I am currently taking Parnate. I once experimented without my doctor's knowledge and tested a single very small dose (less than 10 mg) of Effexor while taking Parnate. I became delirious and experienced muscle rigidity. My parents were concerned to say the least as they witnessed this happening to me. As I became somewhat lucid, I had the wits about me to have them take my temperature. It was a little high for me, but not anything to be concerned with. Had I taken the full 75 mg dose of Effexor, I might not have been so lucky.
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> - ScottUgh, not fun. Good to know, though. MAOIs are tricky.
Tramadol has been a godsend for me. I generally can't tolerate NRIs, but I'm guessing it's the combo of Tramadol's subtle NRI action, along with it being a mild NMDA antagonist, that has helped me so much. I wonder, is that "telling" of anything as far as my biochemistry goes? Additionally, I do well with "clean" SRIs, hence my Lexapro, so it seems I need to keep my serotonin boosted...
poster:brynb
thread:1023975
URL: http://www.dr-bob.org/babble/20120818/msgs/1024103.html