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Re: Lamictal cognitive impairment reversible? » Phillipa

Posted by thegron on August 19, 2012, at 16:30:05

In reply to Re: Lamictal cognitive impairment reversible?, posted by Phillipa on August 19, 2012, at 9:53:12

phidippus,

thanks for your replies. Unfortunately, I cannot take any medication with binding affinity to the 5-HT1a receptor. I have some hypersensitivity autoimmune reaction to them and repeated attempts to take zoloft, prozac, buspar, etc. have left me with severe hyperchlorhydria (acid dyspepsia). I am working with a GI doctor to figure out what the heck happened to me... anyway, they have really f'ed me up. most serotonergic medications act on the 5-HT1a receptor, therefore, i only have a limited number of medications to choose from. that is why I have tried many off-label meds for anxiety. the only meds that have ever worked for me have been benzodiazepines (no longer take them because they caused long lasting cognitive dysfunction) and hydroxyzine (because it only binds to the 5-HT2a receptor). mirtazapine is one of the few AD's that does not bind to the 5-HT1a receptor but for whatever reason, after 6 weeks at 45mg, I felt nothing...

boy i hope my head clears soon....

-Thegron


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URL: http://www.dr-bob.org/babble/20120818/msgs/1023675.html