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Re: Long term efficacy of antipsychotics

Posted by schleprock on August 11, 2012, at 18:36:49

In reply to Re: Long term efficacy of antipsychotics » schleprock, posted by phidippus on August 11, 2012, at 18:26:31

> >My pdoc steered me away from Lyrica, Neurontin, >etc because AAs have antidepressent qualities.
>
> Lyrica and Neurontin are anticonvulsants used to treat epilepsy and off-label to treat anxiety. Neither have any antidepressant qualities.
>
> Geodon is an atypicall antipsychotic which has some antidepressant qualities. One of these antidepressant qualities is that Geodon is an SNRI or seratonin norepenephrine reuptake inhibitor. Geodon is also a 5ht1a partial agonist, which helps treat depression and anxiety.
>
> Latuda is an atypical antipsychotic wwhich also fully agonises 5ht1a receptors, making it a potent antidepressant.
>
> Risperidone is a centrally acting atyipical antipsychotic with high affinity for dopamine receptors. It has no antidepressant qualities.
>
> Your best choices for augmenting antidepressants are Geodon, Seroquel, Abilify and Latuda. Youu shouldn't let the side effects scare you off any medicine.
>
> You're good increasing the dose of a medication if it doesn't seem to be working.
>
> Eric
>
>
>

Thanks. Hypothetically, which of those meds would work best if you have a low dopamine level? From what I understand, Risperidol has a negative effect on dopamine amount.


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poster:schleprock thread:1022971
URL: http://www.dr-bob.org/babble/20120803/msgs/1023059.html